Yes! Absolutely! I actually made another post about this.
make it like this:
NET USE Z: \\ZENTYALSERVER\%USERNAME% in the windows login script.
Personally, I create a batch logon file for each user, and then on the windows server in ADUC I open up their properties, the same place you'd use map home folder, just use login script. They're stored in \\WINDOWS-SERVER-NAME\NETLOGON.
So when you run that script it will replace %username% with their windows login name.
Suchlike:
NET USE Z:\\ZENTYALSERVER\John
NET USE Z:\\ZENTYALSERVER\Jane
As I mentioned in the other post, this is great for me, because I have a client with 15 people, where almost all of them have different shared drives. I use the H: drive to replace their My Documents folder so that they can't lose data in spite of themselves.
One caveat on that topic - some applications, especially anything with the word "Adobe" in it, absolutely hate having a network share as the my docs folder, and you'll have to unmap and remap it to install updates, etc.